Irwig, 2014
“Further research is needed on the subset of men who may be susceptible to 5α-reductase inhibitors.”
Serum androgen levels and semen parameters in 24 PFS patients were reported. 13% were found to have low total testosterone and 13% had low serum DHT. Mean serum androgen levels were close to other studies and could not explain the persistent symptoms.
16% (3 of 19) had severe oligospermia, whereas this finding would be expected in 3% of fertile-age men.